Trauma and emergency surgery, minimally invasive and hepatobiliary surgery, surgical critical care
Principal Investigator: "Open versus Laparoscopic Hernia Repair," National Veterans Administration Cooperative Study, 2000-2004
Principal Investigator: "Long-Term Outcome of Inguinal Hernia Surgery Registry. Open versus Laparoscopic Hernia Repair," National Veterans Administration and American College of Surgeons, 2004-2005.
Principal Investigator: "Metabonomics in Trauma Patients," University of Connecticut, 2004-2007.
Co-Principal Investigator: "Trauma Team Training," United States Air Force, 2005-2007.
Principal Investigator: "Infection Control Strategies to Reduce Colonization and Infection Caused by Anti-microbial Resistant Bacteria in Adult Intensive Care Units," National Institute of Allergy and Infectious Disease, 2005-2008.
Principal Investigator: "Randomized, Multi-Center, Comparative Trial of Short-Course Empiric Antibiotic Therapy versus Standard Antibiotic Therapy for Subjects with Pulmonary Infiltrates in the Intensive Care Unit (ICU)," National Institute of Allergey and Infectious Disease, 2006-2008.
Principal Investigator: "Evaluation of ClotFoam in a Rat Model," Maryland Techonology Development Corporation, 2007-2008.
Program Mentor: T32 Training Grant (Hirshon, JM - PI) University of Maryland, National Institutes of Health, 2007-2010.
Principal Investigator: "Tight Glycemic Control in Critically Injured Trauma Patients," United States Air Force, 2007-2010.
Principal Investigator: “A Prospective Observational Study Evaluating FLEX-HD in Complicated Ventral Hernia Repair,” Musculoskeletal Transplant Foundation, 2007-2010
Co-Principal Investigator: “Blast Injury in Traumatic Brain Injury: Animal Model and Human Volunteer Safety Study,” United States Congressional TBI Fund, 2008-2011.
Principal Investigator: “Biomarkers as a Predictor of Wound Closure,” Office of Naval Research, 2011-2012.
Principal Investigator: “Team Vista”, Department of Veterans Affairs, Greenfield Project, 2010-2012.
Principal Investigator: “Clotfoam Non-Compressible Hemostat,” Department of Defense CDRMP, 2010-2012.
Principal Investigator: "Glyburide Health Volunteer Study," Department of Defense Army Medical Research and Material Command, 2013-2014.
Principal Investigator: "Efficacy of 3-Row Stapler in Lung Resections in Trauma," United States Surgical, 2000-2002.
Principal Investigator: "Efficacy of Costasis Surgical Hemostat in Trauma," Cohesion Technologies, 2000-2002.
Principal Investigator: "Methicillin-resistant Staphylococcus Aureus Acquisition in the Trauma Population," BMS Pharmaceuticals, 2001-2003
Principal Investigator: "Impact of Nosocomial Infections in Trauma," Wyeth Pharmaceuticals, 2001-2005.
Principal Investigator: "PREVENT Study," Merck Pharaceuticals, 2002-2003.
Principal Investigator: "Impact of Johns Hopkins ABX Guide on Critical Care Education. A Randomized Prospective Study," Johnson and Johnson, 2002-2003.
Principal Investigator: "Intra-abdominal infection study, Multi-Institutional Study," Merck Pharmaceuticals, 2003-2006.
Principal Investigator: "Medical Center Case Control Study to Collect Plasma and Whole Blood from ICU Patients at Risk of Sepsis to Identify Biological Markers to Predict Sepsis," BD Diagnostics, 2003-2007.
Principal Investigator: "Topical Use of Blood Products and Sealants," American Red Cross. 2004-2005.
Principal Investigator: "VAP in Trauma Patients," Surgical Infection Society, 2004-2006.
Principal Investigator: "Ventilator Associated Pneumonia Study. Comparison of Doripenem versus Meropenem in Pneumonia Patients," Peninsula Pharmaceuticals, 2004-2007.
Principal Investigator: "EPO-ICU-002 Study: Comparison of Erythropoietin Alpha versus Placebo in Critically Ill Patients," Johnson and Johnson, 2004-2007.
Principal Investigator: "Evaluating Efficacy and Long Term Thrombotic Effects of a Fibrin Bandage in a Swine Model," Johnson and Johnson, 2006-2007.
Principal Investigator: "A Prospective Study to Evaluate the Erythropoietic Responsiveness Associated with Once Weekly (QW) Administration of Darbepoetin Alfa (ARANESP) in Patients Admitted to the Intensive Care Unit," Amgen, 2006-2007.
Principal Investigator: "Evaluation of the Susceptibility of Porcine Submucosa to Various Pathogens (In-Vitro)," Cook Biotech, 2006-2007.
Principal Investigator: "A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Effect of Recombinant Human Erythropoietin (EPOETIN ALFA; PROCRIT), on Function Outcomes in Anemic, Critically Ill, Trauma Subjects," Ortho Biotech, 2006-2009.
Principal Investigator: "Ventilator Associated Pneumonia," Ortho McNeil and Johnson and Johnson, 2007-2008.
Principal Investigator: "Post-Operative Ileus," Wyeth & Tranzyme, 2007-2008.
Principal Investigator: "A Randomized, Double-Blind, Placebo-Controlled, Phase- 2 Study to Assess the Safety and Efficacy Effects of ART-123 on Subjects with Sepsis and Disseminated Intravascular Coagulation," Artisan Pharma, 2007-2008.
Principal Investigator: "Evaluation of Safety and Efficacy of a Fibrin Patch in Soft Tissue Bleeding, A Randomized, Prospective Trial," Johnson and Johnson, 2008-2009.
Principal Investigator: "Evaluating Safety and Efficacy of a Continuous Glucose Monitor," Edwards Life Sciences, 2009-2010.
Principal Investiagor: "Dori-3008 VAP Study," Johnson and Johnson, 2009-2011.
Principal Investigator: "Abthera Open Abdomen Study," KCI, 2009-2012.
Principal Investigator: "Ring, Inguinal Hernia Study," LifeCell, 2009-2012.
Principal Investigator: "Prism, Parastomal Hernia Prevention Study," LifeCell, 2009-2012.
Government - Principal Investigator: "A Randomized Trial of Supplemental Parenteral Nutrition in Under and Overweight Critically Ill Patients: The TOP UP Trial," National Institutes of Health/DHHS, 2013-PRESENT.
Foundation - Principal Investigator: "The Effects of Infection on Hernia Repair Meshes," Barnes Jewish Hospital Foundation, 2013-PRESENT.
Foundation - Principal Investigator: "A Randomized, Prospective, Double-blind, Multi-Center Study to Examine and Compare the Outcomes Associated with the Use of Flex HD, a Human Acellular Dermal Matrix, and Strattice, a Porcine Acellular Dermal Matrix Allograft, When Used as a Reinforcing Material in the Repair of Large Abdominal Wall Hernias by a Component Separation Technique," Musculoskeletal Transplant Foundation, 2013-PRESENT.
Industry - Principal Investigator: "A Non-Investigational Post-Market Trial Using EVARREST Fibrin Sealant Patch as an Adjunct to Hemostasis in Soft Tissue Bleeding During Intra-Abdominal, Retroperitoneal, Pelvic and Non-Cardiac Throacic Surgery," Ethicon, 2013-PRESENT.
Government - Principal Investigator: "A Phase 1, Single-Arm Study Evaluating ClotFoam as an Adjunct Hemostasis in Abdominal Surery in Which Liver Bleeding is Encountered," National Institutes of Health/NHLBI, 2014-PRESENT.
Government - Co-Principal Investigator: "Tranexamic Acid Mechanisms and Pharmacokinetics in Traumatic Injury (TAMPITI Trial)," US Army Medical Research Acquisition Acitivity, 2014-PRESENT.
Government - Principal Investigator: "Recombinant Interleukin-12, a Broad Spectrum Biologic for the Treatment of Battle and Traumatic Wound Infections," Department of Defense, 2014-PRESENT.
Industry - Principal Investigator: "Wound Care Proposal," Cook Biotech, 2014-PRESENT.
Industry - Principal Investigator: "Hemodynamic Instability Rules Based Advisor: The Impact to Care with a New Predictive Indicator," Philips, 2014-PRESENT.
Industry - Principal Investigator: "Manual versus Automated Monitoring Accuracy of Glucose IDE (Manage IDE)," Optiscan, 2014-PRESENT.
Nohra E, Bochicchio GV. Management of the Gastrointestinal Tract and Nutrition in the Geriatric Surgical Patient. Surg Clin North Am. 2015 Feb;95(1):85-101.
Bochicchio G, Gupta N, Porte RJ, Renkens KL, Pattyn P, Topal B, Troisi RI, Muir W, Chetter I, Gillen DL, Zuckerman LA, Frohna PA. The FINISH-3 Trial: A Phase 3, International, Randomized, Single-Blind, Controlled Trial of Topical Fibrocaps in Intraoperative Surgical Hemostasis. J Am Coll Surg. 2015 Jan;220(1):70-81.
Bochicchio GV, Jain A, McGonigal K, Turner D, Ilahi O, Reese S, Bochicchio K. Biologic vs. Synthetic Inguinal Hernia Repair: 1-Year Results of a Randomized Double-Blinded Trial. J Am Coll Surg. 2014 Apr;201(4):751-7.
Bochicchio GV, De Castro GP, Bochicchio KM, Weeks J, Rodriguez E, Scalea TM. Comparison study of acellular dermal matrices in complicated hernia surgery. J Am Coll Surg. 2013 Oct;217(4):606-13.
Fischer CP, Bochicchio G, Shen J, Patel B, Batiller J, Hart JC. A prospective randomized, controlled trial of the efficacy and safety of fibrin pad as an adjunct to control soft tissue bleeding during abdominal, retroperitoneal, pelvic, and thoracic surgery. J Am Coll Surg. 2013 Sep;217(3):385-93.
Cheatham ML, Demetriades D, Fabian TC, Kaplan MJ, Miles WS, Schreiber MA, Holcomb JB, Bochicchio G, Sarani B, Rotondo MF. Prospective study examining clinical outcomes associated with a negative pressure wound therapy system and Barker's vacuum packing techniques. World J Surg. 2013 Sep;37(9):2018-30.
Winfield RS, Bochicchio GV. The critically injured obese patient: a review and a look ahead. J Am Coll Surg. 2013 Jun;216(6):1193-206
Park H, Kent J, Joshi M, Zhu S, Bochicchio GV, Henry S, Scalea T. Percutaneous versus open tracheostomy: comparison of procedures and surgical site infection. Surg Infect (Larchmt). 2013 Feb;14(1):21-3.
Bochicchio G. Preoperative glycemic control in bariatrics and colorectal surgical patients. Ann Surg. 2013 Jan;257(1):15-6.
Crook DW, Walker AS, Kean Y, Weiss K, Cornely OA, Miller MA, Esposito R, Louie TJ, Stoesser NE, Young BC, Angus BJ, Gorbach SL, Peto TE; Study 003/004 Teams. Fidaxomicin versus vancomycin for clostridium difficile infection: meta-analysis of pivotal randomized controlled trials. Clin Infect Dis. 2012 Aug;55 Suppl 2:S93-103.
De Castro GP, Dowling MB, Kilbourne M, Keledjian K, Driscoll IR, Raghavan SR, Hess JR, Scalea TM, Bochicchio GV. Determination of efficacy of novel modified chitosan sponge dressing in a lethal arterial injury model in swine. J Trauma Acute Care Surg. 2012 Apr;72(4):899-907.
Stein DM, Lindell AL, Murdock KR, Kufera JA, Menaker J, Bochicchio GV, Aarabi B, Scalea TM. Use of serum biomakers to predict cerebral hypoxia after severe traumatic brain injury. J Neurotrauma. 2012 Apr 10;29(6):1140-9.
Krinsley J, Bochicchio K, Calentine C, Bochicchio G. Glucose measurement of intensvie care unit patient plasma samples using a fixed wavelength mid-infrared spectroscopy system. J Diabetes Sci Technol. 2012 Mar 1;6(2):294-301.
Bochicchio G, Charlton P, Pezzullo JC, Kosutic G, Senagore A. Ghrelin agonist TZP-101/ulimorelin accelerates gastrointestinal recovery independently of opiod use and surgery type: covariate analysis of phase 2 data. World J Surg. 2012 Jan;36(1):39-45.
Kuehn R, Simard PF, Driscoll I, Keledjian K, Ivanova S, Tosun C, Williams A, Bochicchio G, Gerzanich V, Simard JM. Rodent model of direct cranial blast injury. J Neurotrauma. 2011 Oct;28(10):2155-69.
Pub Med page for Grant V. Bochicchio, MD, MPH
Editorial PositionsJournal Reviewer
2002-present, Journal of Surgical Research
2003-present, Critical Care Medicine
2003-present, Infections in Medicine
2003-present, Surgical Infections
2005-present, Journal of Trauma
2005-present, Journal of the American College of Surgeons
2008-present, Archives of Surgery
Bochicchio G. Retroperitoneal Injury in Trauma. In: Current Therapy of Trauma and Surgical Critical Care. In press, 2007.
Bochicchio G, Scalea T. Hyperglycemia in Surgery. In: Current Therapy of Trauma and Surgical Critical Care; 2008.
Bochicchio G, Scalea TM. Surgical Anatomy of the Abdomen and Regroperitoneum. In: Current Therapy of Trauma and Surgical Critical Care; 2008.
Bochicchio G. Unique Trauma Populations: Obese, Elderly, Pregnant, Adolescent. In: Trauma Surgical Critical Care and Surgical Emergencies; 2008.
Bochicchio G, Scalea T. Glycemic Control in the ICU. In: Advances in Surgery; 2010.